What are the side effects to be expected with the study medicine used in this research study?

Patients have been injected with the study medicine or placebo at several research centres in the United States, Australia and Europe, many of them numerous times. These patients experienced no serious pain or side effects directly related to the injection procedure. However, most medicines have side effects. The medicine used in this study may cause all, some or none of the following:

Drooping of the upper eyelid; pain, discomfort, tearing or itching in the eye; cataract; unequal size of pupils; lowering of the pressure of fluid inside the eye; swelling of the eyelid; bleeding under the conjunctiva; double vision; decreased vision; back pain.

Please note that most of the possible effects above may be caused the injection procedure itself but that they are not serious and none will last. However, patients may experience these effects even if they receive the placebo. Other effects, such as cataract and decreased vision, may also be due to ageing or the progression of the disease.