What will patients need to do during these visits?

The visits will be in the morning will last approximately 4 hours. Patients will have a complete eye examination, including:

• Visual acuity: Patients are asked to read letters on a special eye chart. Visual acuity in the eye that receives the study treatment must be within certain limits, i.e., not too low and no too high.

• Fluorescein angiography: Angiography is a test in which a dye is injected into a vein in the arm. The dye travels throughout the body, including the eyes. With a camera and flash, a series of photographs of the back of the eye is taken as the dye passes through it. The photographs will show where and what kinds of changes have occurred in the retina.

• Indocyanine green (ICG) angiography: This test is similar to fluorescein angiography, described above. However, a different dye is used.

• Routine eye examination: An assessment of the lens, the cornea and the retina will be performed, after drops to dilate the pupils have been administered. Also, the pressure within the eyes will be measured.