In order to be close to the retina, the study medicine will be placed behind the eye by what is called a posterior juxtascleral injection. This is also routinely used for other medicines. Patients do not need to be hospitalised and the whole injection takes about 3 minutes. They are sitting or reclining in an examination chair and a drop of anaesthetic is placed in the eye to suppress pain.  The eye will also be cleaned with a common antiseptic product, as in any surgery of the eye. The doctor makes a very small cut in a thin membrane (the conjunctiva) of the eye but this will not need any stitching.  The study product is injected with a blunt needle (called a cannula) that will be inserted on the side of the eye (Picture 1).  The needle is curved so it will follow the shape of the outside of the eye when it is inserted, without getting inside the eye (Picture 2). When the tip of the needle has reached the back of the eye, the product is injected and the needle taken out (Picture 3). 

Picture 1	Picture 2	Picture 3